These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Surfactant and physiologic alterations in an animal model of adult human lung disease. A preliminary report.
    Author: Sulavik SB, Thrall RS.
    Journal: Respiration; 1987; 51 Suppl 1():10-4. PubMed ID: 2440082.
    Abstract:
    The diffuse obstructive and infiltrative lung diseases (e.g. bronchitis, asthmatic bronchitis, fibrosing alveolitis, sarcoidosis) contribute significantly to human morbidity and mortality. Disturbance of ventilation and perfusion represents a major physiologic defect in these diseases, resulting in pulmonary hypertension, cor pulmonale and right heart failure. Immunologic and surfactant alterations play a prominent role in these diseases. There is a growing body of evidence indicating that surfactant is a most important material in maintaining airway patency. General concepts regarding these functions in human adult lung diseases and results of investigations of surfactant in an animal model of bleomycin-induced lung fibrosis are presented.
    [Abstract] [Full Text] [Related] [New Search]