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  • Title: Fibrosing mediastinitis mimicking sarcoidosis.
    Author: Ferrer Galván M, Rodríguez Portal JA, Serrano Gorarredona MP, Gómez Izquierdo L.
    Journal: Clin Respir J; 2015 Jan; 9(1):125-8. PubMed ID: 24405501.
    Abstract:
    Fibrosing mediastinitis (FM), also called sclerosing mediastinitis or mediastinal fibrosis, is a rare disease characterized by excessive fibrotic reaction in the mediastinum and may compromise the airway, the great vessels and other mediastinal structures, with a morbidity directly related to the location and extent of fibrosis. The cause is not always known but is often the result of a granulomatous disease, most often the histoplasmosis. We report a 43-year-old woman with a history of tuberculosis infection 23 years ago. She attended the pulmonology clinic for cough and dyspnea. Physical examination revealed jugular venous distention at 90°. In computed tomography scan of the chest with contrast (c/c), we observed a mediastinal nodal cast provoking cava compression and obliteration of main and intermediary right lobar bronchus. The pathological examination was FM.
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