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Title: A human monoclonal antibody against HLA-A25. Author: Kosinski S, Ferrara GB, Yang SY, Hämmerling U. Journal: Tissue Antigens; 1987 Apr; 29(4):177-83. PubMed ID: 2441487. Abstract: We are reporting the production and characterization of a human monoclonal antibody recognizing antigen HLA-25. The antibody was developed by a line transformed in vitro by the Epstein-Barr virus. The immune B lymphocytes for transformation were generated by planned immunization of a volunteer with repeated doses of allogenic peripheral blood lymphocytes of one donor over the course of 7 years. The antibody showed correlation with A25 antigen on a panel of 244 individuals tested by microcytotoxicity. The antibody showed neither cytotoxic reactivity nor CYNAP phenomenon with antigens of HLA-10 CREG.[Abstract] [Full Text] [Related] [New Search]