These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: [Relation between gramicidin D and valinomycin-induced conductivity of lipid bilayer and cholesterol levels].
    Author: Hianik T, Bajchi A, Laputkova G, Pavelkova J.
    Journal: Biofizika; 1987; 32(3):458-61. PubMed ID: 2441765.
    Abstract:
    Kinetics of conductance and current-voltage characteristics (VACH) were studied on the bilayer lipid membranes from egg lecithin and cholesterol modified by gramicidin D and valinomycin. There were found significant changes of ionic channels conductance g, lifetime tau and non-linearity coefficient beta of VACH of modified membranes dependent on cholesterol content. In the region of high cholesterol concentrations, more than 20 mol%, there were observed abrupt changes of the ionic channels parameters: tau increased more than ten times, conductance decreased two times and beta greater than 0 in the whole region of electrolyte concentration.
    [Abstract] [Full Text] [Related] [New Search]