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Title: [Relation between gramicidin D and valinomycin-induced conductivity of lipid bilayer and cholesterol levels]. Author: Hianik T, Bajchi A, Laputkova G, Pavelkova J. Journal: Biofizika; 1987; 32(3):458-61. PubMed ID: 2441765. Abstract: Kinetics of conductance and current-voltage characteristics (VACH) were studied on the bilayer lipid membranes from egg lecithin and cholesterol modified by gramicidin D and valinomycin. There were found significant changes of ionic channels conductance g, lifetime tau and non-linearity coefficient beta of VACH of modified membranes dependent on cholesterol content. In the region of high cholesterol concentrations, more than 20 mol%, there were observed abrupt changes of the ionic channels parameters: tau increased more than ten times, conductance decreased two times and beta greater than 0 in the whole region of electrolyte concentration.[Abstract] [Full Text] [Related] [New Search]