These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Involvement of the cell wall ofNocardia restricta on the bioconversions of steroid sapogenins.
    Author: Kastelic-Suhadolc T, Belič I.
    Journal: World J Microbiol Biotechnol; 1991 Jan; 7(1):22-4. PubMed ID: 24424863.
    Abstract:
    The bioconversion of tigogenin, (25R)-5α-spirostan-3β-ol byNocardia restricta to (25R)-4-spirosten-3-one and (25R)-1,4-spirostadien-3-one was strongly increased using protoplasts instead of intact cells. The same effect could be achieved by addingβ-cyclodextrin to the medium. Since 5β-steroid sapogenins pass through the cell wall without hindrance, it can be concluded that the cell wall ofNocardia restricta is a rate-limiting factor only for 5α-isomers.
    [Abstract] [Full Text] [Related] [New Search]