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  • Title: [Nucleic acid content of skeletal muscles during hypokinesia and the recovery period].
    Author: Shibkova DZ, Fomin NA.
    Journal: Kosm Biol Aviakosm Med; 1987; 21(4):28-31. PubMed ID: 2443755.
    Abstract:
    The concentration of nucleic acids in the gastrocnemius muscle of Wistar rats was measured during 60-day hypokinesia and 30-day recovery periods. The data obtained indicate that this hypokinetic model leads to an arrest of muscle growth and inhibition of the age-related accumulation of nucleic acids in the gastrocnemius muscle. The content of DNA and RNA genetic matrixes largely depends on the muscle activity. Normalization of the motor function results in an activation of genetic mechanisms of biosynthesis regulation, acceleration of reparative processes and recovery of muscular activity.
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