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  • Title: Immunohistochemical study on regeneration of substance P-like immunoreactivity in rat molar pulp and periodontal ligament following resection of the inferior alveolar nerve.
    Author: Wakisaka S, Ichikawa H, Nishikawa S, Uchiyama T, Matsuo S, Takano Y, Akai M.
    Journal: Arch Oral Biol; 1987; 32(3):225-7. PubMed ID: 2444197.
    Abstract:
    Using an indirect immunofluorescence method, after 14 days, regenerated SP-containing nerve fibres first appeared around the blood vessels in apical and coronal regions of the pulp and apical and middle regions of the periodontal ligament. Penetration of regenerated SP-positive fibres into the dentine and predentine was observed 25 days after operation. The number of regenerated SP-containing fibres recovered to nearly to the same level as in intact controls by 35 days. They had a similar distribution in the tissues.
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