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  • Title: Clinicopathological aspects of Richter's syndrome.
    Author: Krc I, Macák J, Krcová V, Zahálková J.
    Journal: Folia Haematol Int Mag Klin Morphol Blutforsch; 1987; 114(3):367-75. PubMed ID: 2444510.
    Abstract:
    Richter's syndrome represents an acute transformation of chronic lymphocytic leukaemia or other type of low-grade malignant non-Hodgkin lymphoma to highly malignant anaplastic large-cell lymphoma. The prognosis of this complication is highly unfavourable. The authors report on eight cases of Richter's syndrome observed in a series of 198 patients with the clinical diagnosis of chronic lymphocytic leukaemia and evaluate some clinicopathological and immunological peculiarities of this disease.
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