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  • Title: [Use of the specific rosette formation test in tick-borne encephalitis for the purpose of laboratory diagnosis].
    Author: Minaeva VM, Bykova LP, Parkhomenko TG, Korzukhina LF, Iushkova TA.
    Journal: Zh Mikrobiol Epidemiol Immunobiol; 1987 Jul; (7):41-4. PubMed ID: 2445132.
    Abstract:
    In the study of blood samples collected from patients with tick-borne encephalitis, the modified antigen-specific rosette formation test with erythrocytes, loaded with tick-borne encephalitis virus antigen via the specific immunoglobulin, has been used. The number of rosette-forming cells has been the highest during the acute period of the disease. The use of this test has confirmed the clinical diagnosis of the disease, together with hemagglutination inhibition serving as the main diagnostic test, in 35% of cases. The results of this study make it possible to recommend the antigen-specific rosette formation test for the early diagnosis of tick-borne encephalitis.
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