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  • Title: [Ampicillin pharmacokinetics in prostatic adenoma patients].
    Author: Iakovlev VP, Skala LZ, Slobodskoĭ RA, Nekhorosheva AG, Lur'e LA.
    Journal: Antibiot Med Biotekhnol; 1987 Jul; 32(7):525-8. PubMed ID: 2445279.
    Abstract:
    Studies on ampicillin pharmacokinetics in patients with prostate adenoma showed that adenoma did not influence the antibiotic kinetics. The ampicillin maximum concentration in tissues and organs of the urinary corresponded to the peak concentrations in blood. Therefore, development of dosage regimens providing the drug efficient concentrations in tissues and organs of the urinary tract should be based on ampicillin kinetics in the blood.
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