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Title: Taxol counteracts colchicine blockade of axonal transport in neurites of cultured dorsal root ganglion cells. Author: Horie H, Takenaka T, Ito S, Kim SU. Journal: Brain Res; 1987 Sep 08; 420(1):144-6. PubMed ID: 2445429. Abstract: Taxol does not affect axonal transport in cultured neurites. Preincubation of this drug inhibits the effects of colchicine on axonal transport and morphology in cultured neurites. A reduction of the free tubulin density by preincubated taxol might prevent the disruption of microtubules by colchicine.[Abstract] [Full Text] [Related] [New Search]