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  • Title: Chorea.
    Author: Klawans HL.
    Journal: Can J Neurol Sci; 1987 Aug; 14(3 Suppl):536-40. PubMed ID: 2445458.
    Abstract:
    A variety of neurotransmitters have been implicated in the pathophysiology of chorea as exemplified by Huntington's chorea. These include dopamine, serotonin, acetylcholine, GABA and a variety of neuropeptides including substance P and somatostatin. Despite biochemical data that suggests that alterations in other neurotransmitters may be of greater significance, pharmacologic data still supports a major role of dopamine in the actual clinical manifestation of chorea.
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