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  • Title: Synthesis and cytotoxic activities of a series of novel N-methyl-bisindolylmaleimide amide derivatives.
    Author: Wang K, Liu ZZ.
    Journal: J Asian Nat Prod Res; 2014; 16(3):296-303. PubMed ID: 24456252.
    Abstract:
    A novel series of N-methyl-bisindolylmaleimides were synthesized and evaluated for their inhibitory activities against nine tumor cell lines. Some of the compounds showed an interesting activity against the tested cell lines. The most potent compounds 5e and 5j displayed antiproliferative activity with 50% inhibitory concentration values in the μM range against some tested cell lines.
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