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  • Title: [Macrophage activation syndrome: rare complication of murine typhus].
    Author: Loussaief C, Toumi A, Ben Brahim H, Aouam A, Kairallah M, Chakroun M.
    Journal: Pathol Biol (Paris); 2014 Feb; 62(1):55-6. PubMed ID: 24461392.
    Abstract:
    INTRODUCTION: Typhi is one of the rickettsial species endemic in the Mediterranean countries and is associated with the zoonotic infection of murine typhus, which may have a complicated course especially in adult patients. The association with macrophage activation syndrome (MAS) has rarely been reported in the medical literature. CASE REPORT: We describe a case of murine typhus in a diabetic woman complicated with MAS, who was effectively treated with cyclin and parenteral immunoglobulin. CONCLUSION: The murine typhus can be exceptionally complicated with SAM. This infection should be suspected in front of the discovery of SAM.
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