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  • Title: Clinical effects of intravenous iloprost in patients with intermittent claudication.
    Author: Müller-Bühl U, Diehm C, Krais T, Zimmermann R, Mörl H, Eckstein HH.
    Journal: Eur J Clin Pharmacol; 1987; 33(2):127-31. PubMed ID: 2446877.
    Abstract:
    In a randomized patient-blind study iloprost or hydroxy-ethyl starch 200/0.5 were given i.v. 5 h daily for 2 weeks to 24 patients suffering from severe intermittent claudication due to peripheral vascular disease. An increase in pain-free walking distance of more than 50% occurred in 6 of 11 patients after the iloprost infusions and in 7 of 12 patients after HES treatment. No significant effects on haemodynamic or clinical chemistry tests were observed.
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