These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Neutrophil gelatinase-associated lipocalin after off pump versus on pump coronary artery surgery.
    Author: Lipcsey M, Hayward P, Haase M, Haase-Fielitz A, Eastwood G, Peck L, Matalanis G, Bellomo R.
    Journal: Biomarkers; 2014 Feb; 19(1):22-8. PubMed ID: 24475761.
    Abstract:
    CONTEXT: Cardiac surgery. OBJECTIVE: To compare plasma and urinary neutrophil gelatinase-associated lipocalin (P-/U-NGAL) in on-pump (n = 43) versus off-pump (n = 40) surgery. MATERIALS AND METHODS: We obtained perioperative P-/U-NGAL and outcome data. RESULTS: P-/U-NGAL increased after surgery. P-NGAL was higher post-surgery in on pump patients (139 versus 67 µg L(-1); p < 0.001), but not at 24 h. There were no differences in U-NGAL. Correlation between P-/U-NGAL and plasma creatinine was weak. DISCUSSION: P-NGAL acts like a neutrophil activation biomarker and U-NGAL like a tubular injury marker. CONCLUSION: On-pump patients had greater neutrophil activation. On- versus off-pump surgery had similar impact on tubular cells.
    [Abstract] [Full Text] [Related] [New Search]