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  • Title: Lymphangioma circumscriptum, angiokeratoma, or superficial vascular ectasia with epithelial hyperplasia?
    Author: Katsoulas N, Tosios KI, Argyris P, Koutlas IG, Sklavounou A.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol; 2014 Aug; 118(2):e53-7. PubMed ID: 24491964.
    Abstract:
    We report a case of lymphangioma circumscriptum (cavernous lymphangioma with epithelial hyperplasia) in a 12-year-old girl, presenting as a papillary tumor on the right dorsal side of her tongue. Microscopic examination found cavernous vascular channels lined by a single layer of CD31(+), podoplanin-positive, CD34(-) endothelial cells that occupied the papillary lamina propria and were accompanied by epithelial hyperplasia. A review of the literature on oral vascular tumors with epithelial hyperplasia, namely, lymphangioma circumscriptum and angiokeratoma, provided information that draws into question the use of these terms.
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