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  • Title: [Study on "multi-dimensional structure and process dynamics quality control system" of Danshen infusion solution based on component structure theory].
    Author: Feng L, Zhang MH, Gu JF, Wang GY, Zhao ZY, Jia XB.
    Journal: Zhongguo Zhong Yao Za Zhi; 2013 Nov; 38(21):3622-6. PubMed ID: 24494543.
    Abstract:
    As traditional Chinese medicine (TCM) preparation products feature complex compounds and multiple preparation processes, the implementation of quality control in line with the characteristics of TCM preparation products provides a firm guarantee for the clinical efficacy and safety of TCM preparation products. Danshen infusion solution is a preparation commonly used in clinic, but its quality control is restricted to indexes of finished products, which can not guarantee its inherent quality. Our study group has proposed "multi-dimensional structure and process dynamics quality control system" on the basis of "component structure theory", for the purpose of controlling the quality of Danshen infusion solution at multiple levels and in multiple links from the efficacy-related material basis, the safety-related material basis, the characteristics of dosage form to the preparation process. This article, we bring forth new ideas and models to the quality control of TCM preparation products.
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