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  • Title: Diagnostic accuracy of three biopsy techniques in 117 dogs with intra-nasal neoplasia.
    Author: Harris BJ, Lourenço BN, Dobson JM, Herrtage ME.
    Journal: J Small Anim Pract; 2014 Apr; 55(4):219-24. PubMed ID: 24502380.
    Abstract:
    OBJECTIVES: To determine if nasal biopsies taken at rhinoscopy are more accurate for diagnosing neoplasia than biopsies taken blindly or using advanced imaging for guidance. METHODS: A retrospective study of 117 dogs with nasal mass lesions that were divided into three groups according to the method of nasal biopsy collection; advanced imaging-guided, rhinoscopy-guided and blind biopsy. Signalment, imaging and rhinoscopic findings, and histopathological diagnosis were compared between groups. The proportion of first attempt biopsies confirming neoplasia were determined for each group. RESULTS: There were no statistically significant differences in the proportion of biopsies that confirmed neoplasia obtained via advanced imaging-guided, rhinoscopy-guided or blind biopsy techniques. CLINICAL SIGNIFICANCE: In dogs with a high index of suspicion of nasal neoplasia, blind biopsy may be as diagnostic as rhinoscopy-guided biopsy. Repeated biopsies are frequently required for definitive diagnosis.
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