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  • Title: [Concepts in the prevention and treatment of liver metastases of colorectal cancer by regional chemotherapy].
    Author: Molzahn E, Gruenagel HH, Freund U, Gross D.
    Journal: Chirurg; 1988 Jan; 59(1):34-40. PubMed ID: 2450722.
    Abstract:
    Three different treatments of regional chemotherapy in colo-rectal malignancies and their results are presented. 1. Prophylactic chemotherapy with 5-FU--via the recanalized umbilical vein in patients without liver metastases (randomized study since 10/1980). 2. Intraportal adjuvant chemotherapy after resection of liver metastases. 3. Intraarterial chemotherapy in patients with unresectable liver metastases. The regional chemotherapy of the liver in colo-rectal diseases seems to increase the survival rate and the quality of life. The Port-A-Cath-system can be used repeatedly, however, there is a certain rate of complications to be expected.
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