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  • Title: Synthesis and applications of polyacrylamide grafted agar as a matrix for controlled drug release of 5-ASA.
    Author: Usha Rani G, Konreddy AK, Mishra S, Sen G.
    Journal: Int J Biol Macromol; 2014 Apr; 65():375-82. PubMed ID: 24508089.
    Abstract:
    Agar has been modified by microwave assisted grafting with acrylamide monomer, resulting in poly acrylamide grafted agar (Ag-g-PAM). The synthesized grades of Ag-g-PAM were characterized by standard physico-chemical characterization techniques (FTIR spectroscopy, elemental analysis, scanning electron microscopy (SEM)) to ascertain the intended grafting. The synthesized graft copolymer (Ag-g-PAM) has been investigated (in vitro) for controlled and colon targeted release of 5-amino salicylic acid (5-ASA).
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