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  • Title: [The reproduction in France of Rosen's protocol for osteosarcomas].
    Author: Brunat-Mentigny M, Demaille MC, Quitana E, Olive D, Bachelot C, Boitetot A, Gentet JC, Noir P, Roche H, Thyss JP.
    Journal: Bull Cancer; 1988; 75(2):201-6. PubMed ID: 2451955.
    Abstract:
    The authors treated 188 patients with osteosarcoma by chemotherapy followed by surgery and additional chemotherapy (Rosen's T regimen). In 14% of cases, infectious, neurologic or cardiac complications were observed, which resulted in death in 2% of the patients. Forty-six per cent responded well to the primary chemotherapy, 76% of which are alive and disease-free, as opposed to merely 42% of the bad responders.
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