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Title: How growth due to infant nutrition influences obesity and later disease risk. Author: Brands B, Demmelmair H, Koletzko B, EarlyNutrition Project. Journal: Acta Paediatr; 2014 Jun; 103(6):578-85. PubMed ID: 24521522. Abstract: UNLABELLED: Infant nutrition has a major impact on immediate outcomes and long-term health and later disease risks, such as obesity and related disorders, a phenomenon referred to as 'metabolic programming'. This review discusses the currently postulated hypotheses and mechanisms investigated by the EarlyNutrition project. CONCLUSION: Rapid weight gain in the first 2 years of life, most notably mediated by diary protein, affects the insulin-like growth factor metabolic pathways. Epigenetic processes seem to play a role.[Abstract] [Full Text] [Related] [New Search]