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  • Title: Intravenous thrombolysis is unsafe in stroke due to infective endocarditis.
    Author: Brownlee WJ, Anderson NE, Barber PA.
    Journal: Intern Med J; 2014 Feb; 44(2):195-7. PubMed ID: 24528816.
    Abstract:
    Embolic stroke is the most common neurological complication of infective endocarditis and a major source of morbidity and mortality. Septic embolism is considered a contraindication to intravenous thrombolysis in patients with ischaemic stroke because of concerns over an increased risk of intracranial haemorrhage. We describe a patient with occult endocarditis who was treated with thrombolysis for acute stroke and review other cases reported in the literature.
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