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  • Title: Isolated acute dysphagia due to varicella-zoster virus.
    Author: Mantero V, Rigamonti A, Valentini S, Fiumani A, Piamarta F, Bonfanti P, Salmaggi A.
    Journal: J Clin Virol; 2014 Apr; 59(4):268-9. PubMed ID: 24529416.
    Abstract:
    We present a case of zoster sine herpete causing isolated acute dysphagia in an immunocompetent patient. The interest of this paper is the atypical presentation of varicella-zoster virus reactivation. A 77-year-old woman presented with a 3-day history of fever and worsening dysphagia for both liquid and solid foods. Cerebrospinal fluid examination revealed lymphocytic pleocytosis and PCR amplified varicella-zoster virus DNA with high antibody titers in both serum and cerebrospinal fluid. The panel was suggestive of a cranial neuritis due to varicella-zoster virus, involved cranial nerves, even in the absence of a cutaneous and mucosal rash. Varicella-zoster virus reactivation should be included in the differential diagnosis of isolated or multiple cranial nerve palsies, with or without zosteriform skin lesions. A prompt etiologic diagnosis can lead to early administration of antiviral therapy.
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