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  • Title: Developmentally regulated alternative splicing of brain myelin-associated glycoprotein mRNA is lacking in the quaking mouse.
    Author: Fujita N, Sato S, Kurihara T, Inuzuka T, Takahashi Y, Miyatake T.
    Journal: FEBS Lett; 1988 May 23; 232(2):323-7. PubMed ID: 2454205.
    Abstract:
    Evidence is presented that expression of the two myelin-associated glycoprotein mRNAs is developmentally regulated in mouse brain. In quaking mouse, the mRNA without a 45-nucleotide exon portion was scarcely expressed throughout development. We conclude that the mechanism of splicing out the 45-nucleotide exon portion is lacking in quaking mouse.
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