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  • Title: I-J+ suppressor cells are probably involved in regulation of spleen colony formation by hematopoietic stem cells (CFUs).
    Author: Sanin AV.
    Journal: Biomed Pharmacother; 1987; 41(9-10):477-80. PubMed ID: 2454681.
    Abstract:
    Treatment of murine bone marrow and spleen cell suspensions with anti-I-Jk alloantiserum and complement resulted in an increased number of CFUs (revealed by Till and McCulloch exocolonization technique) compared with controls. The stimulatory effect was observed with 7-8 day CFUs and was negligible or absent with 11-12 day CFUs. Normal thymus cells treated with anti-I-Jk antiserum plus complement would augment the colony-forming potential of normal marrow cells.
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