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Title: A new xanthone from the pericarp of Garcinia mangostana. Author: Fu M, Qiu SX, Xu Y, Wu J, Chen Y, Yu Y, Xiao G. Journal: Nat Prod Commun; 2013 Dec; 8(12):1733-4. PubMed ID: 24555285. Abstract: A new prenylxanthone, garcimangostanol (1), was isolated from the EtOAc-soluble partition of the ethanol extract of the pericarp of Garcinia mangostana L., along with three known compounds, namely 8-deoxygartanin (2), 1-isomangostin (3), and garcinone C (4). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR and MS data. Compounds 1-4 exhibited either significant o r moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines in vitro with IC50 values from 4.0 +/- 0.3 to 23.6+/- 1.5 microM by MTT colorimetric assay.[Abstract] [Full Text] [Related] [New Search]