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  • Title: [Progesterone-induced activation of RNA-binding casein kinase type II during maturation of frog oocytes].
    Author: Stepanov AS, Kandror KV.
    Journal: Mol Biol (Mosk); 1988; 22(2):393-9. PubMed ID: 2455864.
    Abstract:
    During progesterone-induced maturation of the Rana temporaria oocytes phosphorylation of RNA(heparin)-binding proteins changes drastically due to the alterations in the activity of RNA-binding casein kinase II. Its activity increases 7 hr later administration of progesterone and correlates with the level of translation in oocytes. Cycloheximide almost completely inhibits the protein biosynthesis but has no effect on the activity of RNA-binding casein kinase and the set of phosphorylated polypeptides. The possibility is discussed that this enzyme participates in the translation control mechanisms.
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