These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Preparation of a stir bar coated with molecularly imprinted polymer and its application in analysis of dopamine in urine.
    Author: Lei Y, Xu G, Wei F, Yang J, Hu Q.
    Journal: J Pharm Biomed Anal; 2014 Jun; 94():118-24. PubMed ID: 24561337.
    Abstract:
    A molecularly imprinted polymer coated stir bar (MIP-SB) using dopamine as a template was fabricated. The adsorptive capacity of the MIP-SB was almost 4 times over that of non-imprinted stir bar. The MIP-SB showed good extracting selectivity for dopamine when used to adsorb dopamine and its analogs. An analytical method to determine dopamine in urine sample was established by combining MIP-SB sorptive extraction with HPLC-fluorescence detector. The linear range of dopamine concentration was 0.378-18.9ng/ml with correlation coefficient of 0.9990, and the limit of quantification was about 0.0945ng/ml (S/N=10). The recoveries of dopamine with spiked urine samples at three different levels were between 92.3 and 106.9%, and the relative standard deviations were within 13.2% (n=3). The method is simple and suitable for the determination of dopamine in human urine for clinical application.
    [Abstract] [Full Text] [Related] [New Search]