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  • Title: PAF-induced histamine release in the isolated perfused rat kidney.
    Author: Alessandrì MG, Giovannini L, Mian M, Palla R, Gattai V, Ciangherotti A, Bertelli A.
    Journal: Int J Tissue React; 1988; 10(1):33-8. PubMed ID: 2456276.
    Abstract:
    The platelet-activating factor (PAF) has been shown to stimulate the release of prostaglandins, leukotrienes and 5HT from a number of cell types. In this work we studied the effects of bolus injections of PAF on the isolated perfused rat kidney. Results showed histological damage at the proximal-tubule level and a significant histamine release.
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