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  • Title: Alpha interferon treatment of chronic non-A, non-B hepatitis caused by intravenous gammaglobulin.
    Author: Schvarcz R, Weiland O, Glaumann H.
    Journal: Scand J Infect Dis; 1988; 20(2):231-2. PubMed ID: 2456609.
    Abstract:
    Two patients with hypogammaglobulinemia and chronic active non-A, non-B hepatitis caused by intravenous gammaglobulin substitution were treated long-term with alpha-2b interferon (Introna). Both achieved normal aminotransferase levels within 2-12 weeks after initiation of interferon therapy. One patient was rebiopsied after 6 months of therapy and showed some degree of improvement in the liver inflammatory activity. The beneficial effects warrant a randomized controlled study.
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