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  • Title: Fosfomycin susceptibility of canine methicillin-resistant Staphylococcus pseudintermedius isolates.
    Author: DiCicco M, Weese S, Neethirajan S, Rousseau J, Singh A.
    Journal: Res Vet Sci; 2014 Apr; 96(2):251-3. PubMed ID: 24569298.
    Abstract:
    The effectiveness of fosfomycin was examined across 31 methicillin-resistant Staphylococcus pseudintermedius (MRSP) strains by agar dilution. Prevalence of the fosfomycin-resistance determinant gene, fosB, was assessed by PCR analysis. Results found that 84% of isolates were fosfomycin-susceptible. Interestingly, 87% of isolates possessed fosB, indicating no association between this putative staphylococci resistance gene and phenotypic resistance. Further evaluation of fosfomycin as a potential treatment of MRSP in dogs is warranted.
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