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  • Title: Microwave-assisted preparation of azachalcones and their N-alkyl derivatives with antimicrobial activities.
    Author: Usta A, Öztürk E, Beriş FŞ.
    Journal: Nat Prod Res; 2014; 28(7):483-7. PubMed ID: 24571646.
    Abstract:
    Two new azachalcones were prepared by both Claisen-Schmidt condensation and a simple environmentally trendy microwave-assisted method. Ten new N-alkyl (C6,8,10,12,14)-substituted azachalconium bromides (3a-e, 4a-e) were prepared from compounds 1 and 2 with corresponding alkyl halides. The antimicrobial activities of all the compounds were tested against Enterococcus faecalis, Yersinia pseudotuberculosis, Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus micro-organisms.
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