These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Fluoroaluminates stimulate histamine secretion in the digitonin-permeabilized rat mast cells.
    Author: Sorimachi M, Nishimura S, Yamagami K, Yada T.
    Journal: Jpn J Physiol; 1988; 38(2):227-32. PubMed ID: 2459433.
    Abstract:
    The combination of NaF and AlCl3 stimulated histamine secretion from digitonin-permeabilized rat mast cells only in the presence of trace amount of Ca2+. When NaF plus AlCl3 were added together with a maximal dose of guanosine-5'-[gamma-thio]triphosphate (GTP gamma S), the combined effect was less than additive. The results suggest that the secretory effect of fluoroaluminates is, at least partially, mediated by GTP-binding protein, which is previously found to be activated by GTP gamma S.
    [Abstract] [Full Text] [Related] [New Search]