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  • Title: A new periplogenin cardenolide from the seeds of Antiaris toxicaria.
    Author: Wu XL, Wu YL, Li HG, Liu HT, Fu XY, Cui RQ, Wang JH, Liu C, Chen J.
    Journal: J Asian Nat Prod Res; 2014; 16(4):418-21. PubMed ID: 24597720.
    Abstract:
    A new periplogenin cardenolide, periplogulcoside (1), together with three known cardenolides, was isolated from the seeds of Antiaris toxicaria. The structure of the new compound was characterized as periplogenin-3-O-β-D-glucopyranosyl-(1 → 4)-β-D-glucopyranoside (1) by spectroscopic methods including 1D and 2D NMR, HR-TOF-MS, and CD spectrometry, and the known compounds were identified by comparison of their NMR and HR-TOF-MS data with those reported in the literature. Compound 1 showed significant cytotoxicity against Hela and HepG-2 cell lines.
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