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  • Title: [Effect of inhibitors that destroy cytoskeleton structures on the antiviral and antiproliferative activity of interferons].
    Author: Solov'eva MF, Krispin TI, Shloma DV, Kalmakhelidze KA, Balandin IG.
    Journal: Vopr Virusol; 1988; 33(3):309-14. PubMed ID: 2459850.
    Abstract:
    The effect of a number of drugs (vincristine, vinblastine, cytochalasin B, colcemid, colchamine) destroying cytoskeleton structures (microtubules and microfilaments) in combination with homologous interferon was studied in L920 and CaOv cells. The above substances were shown to inhibit the antiviral and enhance (from additivity to synergism) the antiproliferative effect of interferons under study.
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