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  • Title: Voltage-gated currents recorded from the surface of the frog optic nerve.
    Author: Ortiz S, Rodriguez O, Orkand PM, Orkand RK, Marrero H.
    Journal: P R Health Sci J; 1988 Aug; 7(2):141-3. PubMed ID: 2460888.
    Abstract:
    Macroscopic voltage-dependent currents were recorded from the surface of the intact optic nerve of Rana pipiens using the loose patch clamp technique. Depolarizing steps of more than 40 mV produced sodium-dependent TTX sensitive inward currents and a 4-AP and sodium sensitive fast outward current in addition to a slower outward current. Since the surface of the nerve is a glia limitans, it appears that the membranes of these astrocytes contain both voltage-sensitive sodium and potassium channels.
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