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  • Title: [Comparative studies of bronchial secretions in children with chronic, nontuberculous lung diseases. 3. The detection of lysozyme, transferrin, alpha 1-antitrypsin, alpha 2-macroglobulin, haptoglobin and alpha 1-acid glycoprotein].
    Author: Stelzner A, Groh A, Lehnert U.
    Journal: Allerg Immunol (Leipz); 1988; 34(2):99-108. PubMed ID: 2461066.
    Abstract:
    In 166 bronchial secretions from 63 children with chronic nontuberculous lung diseases lysozyme, transferrin, alpha 1-antitrypsin, alpha 2-macroglobulin, haptoglobin and alpha 1-acid glycoprotein were estimated. In patients with hard bronchoscopic or bronchographic alterations a reduction of lysozyme, alpha 1-antitrypsin and alpha 2-macroglobulin could be found. These proteins were measured more frequently in cases with dark altered mucosa. Moreover no relation could be found between transferrin, alpha 1-antitrypsin and alpha 2-macroglobulin and the outbreak of the diseases. -In bacterial contaminated secretions transferrin could be demonstrated more frequently in comparison with sterile bronchial secretions.
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