These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Palladium-catalyzed decarboxylative trifluoroethylation of aryl alkynyl carboxylic acids.
    Author: Hwang J, Park K, Choe J, Min H, Song KH, Lee S.
    Journal: J Org Chem; 2014 Apr 04; 79(7):3267-71. PubMed ID: 24628537.
    Abstract:
    A trifluoroethylation of alkynes through a palladium-catalyzed decarboxylative coupling reaction was developed. When alkynyl carboxylic acids and ICH2CF3 were allowed to react with [Pd(η(3)-allyl)Cl]2/XantPhos and Cs2CO3 in N,N-dimethylformamide (DMF) at 80 °C for 1 h, the desired products were formed in good yields. This catalytic system showed high functional group tolerance.
    [Abstract] [Full Text] [Related] [New Search]