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  • Title: Macrophage activation syndrome in Kawasaki disease.
    Author: Mukherjee D, Pal P, Kundu R, Niyogi P.
    Journal: Indian Pediatr; 2014 Feb; 51(2):148-9. PubMed ID: 24632699.
    Abstract:
    BACKGROUND: Kawasaki disease is an acute febrile vasculitis of childhood. Macrophage activation syndrome is a rare life threatening complication. CASE CHARACTERISTICS: 4-year-old boy with Kawasaki Disease treated with intravenous immunoglobulins. OBSERVATION: He developed encephalopathy, hepatosplenomegaly and pancytopenia. Blood investigations and bone marrow aspiration suggested macrophage activation syndrome. OUTCOME: Good response to pulse methylprednisolone (30 mg/kg/d) for 5 days. MESSAGE: Macrophage activation syndrome may complicate Kawasaki disease.
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