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  • Title: Anabolic steroid-induced hypogonadism: diagnosis and treatment.
    Author: Rahnema CD, Lipshultz LI, Crosnoe LE, Kovac JR, Kim ED.
    Journal: Fertil Steril; 2014 May; 101(5):1271-9. PubMed ID: 24636400.
    Abstract:
    OBJECTIVE: To develop an understanding of hypogonadal men with a history of anabolic-androgenic steroid (AAS) use and to outline recommendations for management. DESIGN: Review of published literature and expert opinions. Intended as a meta-analysis, but no quality studies met the inclusion criteria. SETTING: Not applicable. PATIENT(S): Men seeking treatment for symptomatic hypogonadism who have used nonprescribed AAS. INTERVENTION(S): History and physical examination followed by medical intervention if necessary. MAIN OUTCOME MEASURES(S): Serum testosterone and gonadotropin levels, symptoms, and fertility restoration. RESULT(S): Symptomatic hypogonadism is a potential consequence of AAS use and may depend on dose, duration, and type of AAS used. Complete endocrine and metabolic assessment should be conducted. Management strategies for anabolic steroid-associated hypogonadism (ASIH) include judicious use of testosterone replacement therapy, hCG, and selective estrogen receptor modulators. CONCLUSION(S): Although complications of AAS use are variable and patient specific, they can be successfully managed. Treatment of ASIH depends on the type and duration of AAS use. Specific details regarding a patient's AAS cycle are important in medical management.
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