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  • Title: [Production of the monoclonal antibodies to the rabies virus nucleoprotein].
    Author: Gribencha SV, Kozlov AIu, Kostina LV, Elakov AL, Losich MA, Tsibezov VV, Zaberezhnyĭ AD, Aliper TI.
    Journal: Vopr Virusol; 2013; 58(5):38-43. PubMed ID: 24640170.
    Abstract:
    Five hybridomas secreting monoclonal antibodies (MAbs) for the nucleocapsid protein of the rabies virus were obtained through the fusion of the SP2/0 murine myeloma cells with splenocytes of BALB/c mice immunized with fixed rabies virus (CVS strain). All hybridomas secret MAbs of the IgG class that display different specificity to the nucleocapsids of rabies and rabies-related viruses. MAbs 2ell showed the specificity for the prevalent in Russia rabies viruses that are similar to commercially available anti-rabies conjugate.
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