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  • Title: A case of septal panniculitis secondary to interferon treatment.
    Author: Ozuguz P, Kacar SD, Karaca S, Tokyol C.
    Journal: Cutan Ocul Toxicol; 2014 Dec; 33(4):351-2. PubMed ID: 24641120.
    Abstract:
    The most common side effects of interferon-beta therapy following subcutaneous administration include pain, inflammation and induration at the injection site, which occur in approximately 20-60% of patients. Besides, transient injection-site erythema is frequently seen in beta-interferon therapy. Less frequent reactions at injection sites include vascular thrombosis, mucinosis, dermal and systemic sclerosis, necrosis, and ulceration. Here, we report a 44-year-old case diagnosed with multiple sclerosis, who developed pain and swelling following interferon-beta 1a treatment after an improperly administered intramuscular injection; and with this case report, we would like to draw attention to septal panniculitis, a serious drug complication, that develops following interferon-beta 1a treatment after an improperly administered intramuscular injection.
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