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  • Title: Management of tardive syndromes with clozapine: a case series.
    Author: Grover S, Hazari N, Kate N, Chakraborty K, Sharma A, Singh D, Gupta J, Lahariya S.
    Journal: Asian J Psychiatr; 2014 Apr; 8():111-4. PubMed ID: 24655641.
    Abstract:
    Tardive syndromes are among the most debilitating side effects associated with use of antipsychotics. In this case series we present 5 cases of drug induced tardive syndromes, who had not responded to many of the other therapeutic measures but responded to clozapine. The response rate with clozapine varied from 50% to 100% and the response was seen by week 3 in most cases. Over the long term follow-up of as long as 6 years the response to clozapine was sustained. In two cases clozapine could be stopped.
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