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  • Title: [Rituximab for treatment of Felty’s syndrome].
    Author: Becker H, Appel H, Fassbinder T, Heitzmann D, Willeke P, Jacobi AM.
    Journal: Z Rheumatol; 2014 Jun; 73(5):465-6, 468. PubMed ID: 24659095.
    Abstract:
    Felty’s syndrome is a rare variant of severe seropositive rheumatoid arthritis with neutropenia and splenomegaly. It is difficult to treat and associated with a poor prognosis due to the substantial risk of infections. This article presents the case of a patient with refractory disease who responded to rituximab with permanent normalization of neutrophil counts. Repeated infusions were necessary to induce and maintain remission.
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