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  • Title: Partial splenectomy for treatment of chronic idiopathic thrombocytopenia in childhood.
    Author: Specht U, Mau H, Winter H, Jahn S, Volk H, Cario WR.
    Journal: Folia Haematol Int Mag Klin Morphol Blutforsch; 1988; 115(4):509-14. PubMed ID: 2465963.
    Abstract:
    The aim of this paper was to demonstrate the efficiency of partial splenic resection in treatment of chronic idiopathic thrombocytepenie purpura (Werlhof-Disease). In all but one case remissions of thrombocyte counts over 100 Gpt/l could be achieved. Immunological studies demonstrate the existence of a suppressor-state after this operation, which could be responsible for success of this procedure. In contrast to general considerations the partial-splenectomized child must be considered as an immunological deficient organism for about 6 to 12 months. Restoration of immunological-means whole splenic functions-parameters is to expect always after this time.
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