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  • Title: Diagnostic value of immunoreactive phospholipase A2 in acute pancreatitis.
    Author: Malfertheiner P, Nevalainen T, Uhl W, Schädlich H, Büchler M.
    Journal: Klin Wochenschr; 1989 Feb 01; 67(3):183-5. PubMed ID: 2467045.
    Abstract:
    In a prospective clinical trial 85 patients with acute pancreatitis were analysed for serum total amylase, pancreatic amylase, pancreatic lipase, trypsin, elastase 1, and immunoreactive phospholipase A2 (IR-PLA2). The diagnostic sensitivity of serum IR-PLA2 was comparable to that of serum total amylase, pancreatic amylase, and trypsin. The specificity of IR-PLA2 is superior to that of serum total amylase determination due to the fact that the IR-PLA2 determination is based on an antibody against human pancreatic PLA2.
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