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  • Title: Second-look laparotomy in endodermal sinus tumor: a report of two patients with normal levels of alpha-fetoprotein and residual tumor at reexploration.
    Author: Curtin JP, Rubin SC, Hoskins WJ, Hakes TB, Lewis JL.
    Journal: Obstet Gynecol; 1989 May; 73(5 Pt 2):893-5. PubMed ID: 2468119.
    Abstract:
    The role of second-look laparotomy in the management of patients with endodermal sinus tumor of the ovary is controversial. We report two women who converted to a normal alpha-fetoprotein (AFP) level during treatment with combination chemotherapy, yet were found to have residual endodermal sinus tumor at second-look laparotomy. In view of the limited experience with this rare disease, we continue to recommend second-look laparotomy for patients who have completed chemotherapy for endodermal sinus tumor of the ovary, regardless of the serum AFP level.
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