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  • Title: [Furosemide-sensitive cation transport in frog skeletal muscle fibers].
    Author: Vinogradova TA, Marakhova II.
    Journal: Tsitologiia; 1988 Oct; 30(10):1200-7. PubMed ID: 2469239.
    Abstract:
    Furosemide-inhibitable components in unidirectional cation fluxes have been identified in frog skeletal muscle. In sodium loaded muscles, placed in sodium-free rubidium lithium media, furosemide (1 mM) inhibits partially rubidium and lithium influxes as well as potassium and sodium outfluxes. The furosemide-inhibitable components were found to depend on the presence of ouabain. They were greatly diminished in sodium-free magnesium media and were present in chloride-free nitrate containing media. The dependence of furosemide-inhibitable sodium efflux on internal sodium content was also described.
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